1. Right-click a shortcut on the desktop or in the start menu, and then click Properties .
2. On the Shortcut tab, click in the Shortcut Key box.
3. Press the key you want to use. Windows will add Ctrl+Alt to it. So if you choose U the combination will be Ctrl+Alt+U.You can also choose one of the function keys you don't use otherwise, F7 as example. Just one button to click then.
4. Click OK .